TOOTH REGROWING

Researchers at the Tokyo University of Science have successfully transplanted a bioengineered tooth into the mouth of an adult mouse.

Presentation  ICA/ASA, Seattle WA When people think of ultrasound, they usually think of prenatal exam-fuzzy pictures prized by new parents. Ultrasound has achieved great success in diagnostic imaging because it is safe, portable, and less expensive than other forms of medical imaging. A less well-known fact is that at much higher intensities, the same acoustic waves used in diagnostic imaging can be used therapeutically. Higher-intensity ultrasound can interact with tissue to generate heat, mechanical energy.

According to the U.S. Department of Health and Human Services, the average American will lose about eight teeth by the time he or she turns 50. Common replacements include dentures, which have been known to erode the underlying bone over time, and dental implants, which are prone to falling out after several years' use. Thus, the ability to regrow a natural tooth, with the accompanying bone, root, and nerves, could provide a significantly healthier alternative for all.

This is about our eighteen month test of using LIPUS to regrow pulp and dentin at an accelerated rate for mature and senior people. The process invigorates the inside of our teeth for increased healthier tissue. The added growth of dentin bolsters the enamel as it was when you were a younger person.

In addition to the above an increase of density in mandible bone and upper tooth support solidifies tooth roots. Our experience shows a solid bite equal to that in our teenage years. The ringing of teeth when biting down hard, which we had forgotten entirely, was back again.

Professor Paul Sharpe, Head of the Department of Craniofacial Development, King’s College London stated: “A key medical advantage of this new technology is that a living tooth can preserve the health of the surrounding tissues much better than artificial prosthesis. Teeth are living, and they are able to respond to a person’s bite. They move, and in doing so they maintain the health of the surrounding gums and teeth.”

At the present time our technology is at the stage where regrowing teeth is limited to teeth with live roots. The inner part of the tooth, dentin is alive and in regrowing will expand into its initial, youthful proportions. The dentin thereby puts equal pressure on the Enamel part of the tooth as in the younger person. This naturally recurring rejuvenation has a propensity to expel such parts of the tooth enamel which have previously been broken, which may result in its loss.

Our experience is based on our use of this methodology and equipment over a period of eighteen month. Any person planning to use this Canadian LIPUS technique can inquire with questions to our test section. A two day seminar with hands on training is a requirement to assure success. Guarantee of your success is available conditional on you providing X-ray photos of your teeth at the beginning of the seminar.

Excluded from these guarantees are charges for equipment provided, travel expense and hotel/motel and all other related items.

If you have an understanding of the function of the LIPUS application you are free to join our research program by contributing research funds to LIPUS LLC and join in broadening our experience. An illustrated manual and LIPUS equipment is supplied to you at a time when back logs have been filled. Please remember that questions will have to be E-mailed to the address below. Please always include name and address. At this time LIPUS service is limited to people living on the North American continent.

E-MAIL ADDRESS: edu@lipus.org

Presented Tuesday morning, June 23, 1998

ICA/ASA '98, Seattle WA

Ultrasound is usually thought of as prenatal exams-fuzzy videotapes prized by new parents. Ultrasound equipment has achieved great success in diagnostic imaging because it is safe, portable, and less expensive than other forms of medical imaging.

A less well-known fact is that at much higher intensities, the same acoustic waves used in diagnostic imaging can be used therapeutically. High-intensity ultrasound can interact with tissue to generate heat and mechanical energies that increase blood flow. Increased blood flow benefits are oxygenation of organs and removal of dead tissue. Our body rebuilds itself constantly. We associate a reduction of this process as aging and reduction of our health.

Recently, a Japanese team from the Tokyo University of Science, led by associate professor Takashi Tsuji, reported in Nature Methods that it had successfully re-grown a tooth from cells extracted from mouse embryos. The researchers were able to transplant the tooth into an adult mouse, and the tooth bud continued to grow to full size.

Teeth in mice, much like those in humans, form during embryonic development from two major cell types: epithelial and mesenchymal. Epithelial cells give rise to the outer enamel, while mesenchymal cells form a tooth's inner connective tissue and blood vessels.

Takashi's team isolated both kinds of cells from multiple mouse embryos, then transferred them to a collagen gel culture, in which the cells interacted to form a tooth bud. Researchers then transplanted the bud into the liver of an adult mouse, where the increased blood supply aided further tooth formation. Finally, Takashi inserted the tooth into an empty cavity within the mouse's mouth, in which it grew to full size.

 Ultrasonic for tooth regrowth.

A team at the University of Alberta have miniaturized a technology called low intensity pulsed ultrasound (LIPUS) The regenerative effect of LIPUS was discovered by Dr Tarak El-Baily while working on rabbit subjects. The inducer is targeted to "massage" the root of a tooth injured either mechanically or by disease. It stimulates new growth and counteracts the destructive process of dental resorption, which often means a damaged tooth has to be completely removed.

Before El-Baily collaborates with circuit design specialists to shrink the device to smaller than a pea, our test subjects had to hold a large LIPUS source to their mouth for 20 minutes daily for a whole year.

It's envisaged that the device could also be deployed to treat microsomia, a congenital underdevelopment of the lower jaw.

For use of the LIPUS effect an appointment for a training session can be arranged. At the initiation phase this training is limited to locations on the American continent. The training is done by the scientific researcher with hands on experience from developing methods and equipment with visible and proven results.

Our experience shows that results are expected to arrive gradually at latest between eighteen and twenty six months. Being able to use the methods on schedule at home in accordance with instructions is the only way to guarantee success.

Half a million Americans sought medical care abroad in 2006, of which 40 percent were dental tourists, according to the National Coalition on Health Care, an alliance of more than 70 organizations. That’s up from an estimated 150,000 in 2004, said Renee-Marie Stephano, the chief operating officer for the Medical Tourism Association, a nonprofit organization that researches global health care.

Dental bridges and bonding ranked No. 1 and 2 on a list of most sought-after procedures for Americans traveling abroad for medical care, according to a report just published by HealthCare Tourism International, a nonprofit group that tracks health care.

Your oral health affects your general health and vice versa.

There are two main groups of family-oriented dental travelers, said Neil Patel, the founder of HealthCare Tourism International. Immigrants have long returned to their countries of origin for dental and medical care and to spend time with relatives. But now there’s a more recent wave of patients, interested in taking their families to a far-flung location to make the best out of what is essentially a rather unpleasant chore.

The advanced technology of making your body rebuild most of your damaged teeth as a first step, and with hope of soon having Americans able to regrow teeth together with their mandibular bone may well create havoc for the foreign dental industry.

Question is how long will it take Americans with problematic teeth to transfer to this Canadian LIPUS treatment? Easily obtained at home at a fraction of the cost of treatment and travel abroad, with patients maintaining control it will create an advantage in the area where Americans rarely have insurance, or only at insanely high cost.

Also how is this going to make the North American continent the new travel destination for people with dental trouble across the world? Not to forget that LIPUS  may well become the future’s drugless healing method of the world once the success of its application has spread widely to be recognized as a superior treatment to all we have heretofore been taken to be the best.

At a time of more frequent recalls for pharmaceutical products because of dangerous side effects here at home the advent of drugless treatment is alluring to us all.

SOT foundation is a research consortium targeting worldwide scientific development of DRUGLESS slowing and reversing tooth, muscle and bone deterioration.

Mr. Matuschka who has tested the LIPUS system developed in Edmonton Alberta with results written up above. At present Mr. Matuschka has funded all research here in the US at his LIPUS foundation's location in Colorado.

Mr. Matuschka’s second stage project is to find one hundred people to join him to test in numbers what he has established in the period from August 2006 to the present. A limited number of research and funding members will be provided with progressive findings on a monthly basis.

Funding associates will have options to join in the testing member group as feasible. The test is on a first come first joined. Testing members will have to provide X-rays for comparison of before and after application.

The contents of the LIPUS foundation website and responses are for informational purposes only. The information contained on our Website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. If you have any questions regarding a medical condition or illness, you should always seek the advice of your physician or other qualified health care professional. Never disregard professional medical advice or delay in seeking advice or treatment because of information you have read on our website. If you think that you may have a medical emergency or other condition that requires treatment, call your doctor or seek emergency help immediately. Reliance on any information provided by lipus foundation is solely at your own risk.