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Researchers at the Tokyo University of Science have successfully transplanted a bio-engineered tooth into the mouth of an adult mouse.


ICA/ASA, Seattle WA

When people think of ultrasound, they usually think of prenatal exam-fuzzy pictures prized by new parents. Ultrasound has achieved great success in diagnostic imaging because it is safe, portable, and less expensive than other forms of medical imaging.
A less well-known fact is that at much higher intensities, the same acoustic waves used in diagnostic imaging can be used therapeutically. Higher-intensity ultrasound can interact with tissue to generate heat, mechanical energy.


According to the U.S. Department of Health and Human Services, the average American will lose about eight teeth by the time he or she turns 50. Common replacements include dentures, which have been known to erode the underlying bone over time, and dental implants, which are prone to falling out after several years' use. Thus, the ability to regrow a natural tooth, with the accompanying bone, root, and nerves, could provide a significantly healthier alternative for all.

This is about our fifty fourth month test of using LIPUS to regrow pulp, dentin, and possible cementum at an accelerated rate for mature and senior people. The process invigorates the inside of our teeth for increased healthier tissue. The added growth of dentin bolsters the enamel as it was when you were a younger person.

In addition to the above an increase of density in mandible bone and upper tooth support solidifies tooth roots. Our experience shows a solid bite equal to that in our teenage years. The ringing of teeth when biting down hard, which we had forgotten entirely, was back again.

Professor Paul Sharpe, Head of the Department of Craniofacial Development, King’s College London stated: “A key medical advantage of this new technology is that a living tooth can preserve the health of the surrounding tissues much better than artificial prosthesis. Teeth are living, and they are able to respond to a person’s bite. They move, and in doing so they maintain the health of the surrounding gums and teeth.”

At the present time our technology is at the stage where regrowing teeth is limited to teeth with live roots. The inner part of the tooth, dentin is alive and in regrowing will expand into its initial, youthful proportions. The dentin thereby puts equal pressure on the Enamel part of the tooth as in a younger person. This naturally recurring rejuvenation has a propensity to expel such parts of the tooth enamel which have previously been broken, which may result in its loss.

An illustrated manual and LIPUS equipment can be ordered by you if you want to obtain the benefits of LIPUS application. Any questions to be E-mailed to the address below. Please always include your name and address.

Lipus-Plasma, application units;
Transformer, Timer, Electronics, Casing, Transducer included, in one shell
Shipping, handling and insurance, paid by user.   Lipus units with 4 year warranty.


                                                    X-ray taken by Dr. Chavez after 1 year of LIPUS use


                                                                                                Click on envelope

Presented Tuesday morning, June 23, 1998

ICA/ASA '98, Seattle WA

Ultrasound is usually thought of as prenatal exams-fuzzy videotapes prized by new parents. Ultrasound equipment has achieved great success in diagnostic imaging because it is safe, portable, and less expensive than other forms of medical imaging.

A less well-known fact is that at much higher intensities, the same acoustic waves used in diagnostic imaging can be used therapeutically. High-intensity ultrasound can interact with tissue to generate heat and mechanical energies that increase blood flow. Increased blood flow benefits are oxygenation of organs and removal of dead tissue. Our body rebuilds itself constantly. We associate a reduction of this process as aging and reduction of our health.

Recently, a Japanese team from the Tokyo University of Science, led by associate professor Takashi Tsuji, reported in Nature Methods that it had successfully re-grown a tooth from cells extracted from mouse embryos. The researchers were able to transplant the tooth into an adult mouse, and the tooth bud continued to grow to full size.

Teeth in mice, much like those in humans, form during embryonic development from two major cell types: epithelial and mesenchymal. Epithelial cells give rise to the outer enamel, while mesenchymal cells form a tooth's inner connective tissue and blood vessels.

Takashi's team isolated both kinds of cells from multiple mouse embryos, then transferred them to a collagen gel culture, in which the cells interacted to form a tooth bud. Researchers then transplanted the bud into the liver of an adult mouse, where the increased blood supply aided further tooth formation. Finally, Takashi inserted the tooth into an empty cavity within the mouse's jaw, in which it grew to full size.


 Ultrasonic for tooth regrowth.

A team at the University of Alberta have miniaturized a technology called low intensity pulsed ultrasound (LIPUS) The regenerative effect of LIPUS was discovered by Dr Tarak El-Baily while working on rabbit subjects. The inducer is targeted to "massage" the root of a tooth injured either mechanically or by disease. It stimulates new growth and counteracts the destructive process of dental resorption, which often means a damaged tooth has to be completely removed.

Subjects hold a  LIPUS source to their mouth twice a day for 1 LIPUS unit timing cycle.

It's envisaged that the device could also be deployed to treat microsomia, a congenital underdevelopment of the lower jaw.

Our experience shows that results are expected to arrive gradually at latest between eighteen and twenty six months. Being able to use the methods on schedule at home in accordance with instructions is the only way to expect success.

Half a million Americans sought medical care abroad in 2006, of which 40 percent were dental tourists, according to the National Coalition on Health Care, an alliance of more than 70 organizations. That’s up from an estimated 150,000 in 2004, said Renee-Marie Stephano, the chief operating officer for the Medical Tourism Association, a nonprofit organization that researches global health care.

Dental bridges and bonding ranked No. 1 and 2 on a list of most sought-after procedures for Americans traveling abroad for medical care, according to a report just published by HealthCare Tourism International, a nonprofit group that tracks health care.

Your oral health affects your general health and vice versa.

Keeping your gums in good shape, may go a long way toward protecting your heart health. Although still in the early stages, research presented at the American Heart Association Scientific Sessions 2011 in Orlando, Fla., this week shows a tantalizing link between gum disease and heart disease.

In one study, periodontist Anders Holmlund, of Gävle, Sweden, found that some types of gum disease, such as those that cause tooth loss or bleeding gums, could increase the likelihood of heart attack, stroke or heart failure.

It has also been found that one of the effects of using the LIPUS equipment, alleviates, and in some cases totally eliminates, halitosis.  The same has also been observed for
infections in teeth and roots.

They found that:

  • Adults with fewer than 21 teeth (adults normally have 32 teeth, including four wisdom teeth) had a 69 percent increased risk of heart attack compared with adults who retained most of their teeth.
  • People with more infected areas where the gums pull away from the teeth, called periodontal pockets, had a 53 percent greater risk of a heart attack than those with the fewest pockets.
  • Adults who had the fewest teeth had double the risk of developing congestive heart failure — when a weakened heart can't pump enough blood — compared with those who retained more of their teeth.
  • Men and women who suffered from bleeding gums had more than twice the risk of stroke compared with those whose gums were healthy.

There are two main groups of family-oriented dental travelers, said Neil Patel, the founder of Health-Care Tourism International. Immigrants have long returned to their countries of origin for dental and medical care and to spend time with relatives. But now there’s a more recent wave of patients, interested in taking their families to a far-flung location to make the best out of what is essentially a rather unpleasant chore.

The advanced technology of making your body rebuild most of your damaged teeth as a first step, and with hope of soon having Americans able to regrow teeth together with their mandibular bone may well create havoc for the foreign dental industry.

Question is how long will it take Americans with problematic teeth to transfer to this Canadian LIPUS treatment? Easily obtained at home at a fraction of the cost of treatment and travel abroad, with patients maintaining control it will create an advantage in the area where Americans rarely have insurance, or only at insanely high cost.

Also how is this going to make the North American continent the new travel destination for people with dental trouble across the world? Not to forget that LIPUS  may well become the future’s drug-less healing method of the world once the success of its application has spread widely to be recognized as a superior treatment to all we have heretofore been taken to be the best.

At a time of more frequent recalls for pharmaceutical products because of dangerous side effects here at home the advent of drugless treatment is alluring to us all.

SOT foundation is a research consortium targeting worldwide scientific development of DRUGLESS slowing and reversing tooth, muscle and
bone deterioration.

Applications of LIPUS include:

    Promoting bone fracture healing.

    Treating orthodontically induced root resorption.
    Regrow missing teeth.

    Enhancing mandibular growth in children with hemifacial microsomia.

    Promoting healing in various soft tissues such as cartilage, inter vertebral disc, etc.

    Improving muscle healing after laceration injury.

         Lipus On                           Lipus Low                           Lipus High                         Lipus
          High Half                                                 

              Power Panel Settings at various levels as shown in manual.

Mr. Matuschka  has tested the LIPUS system developed in Edmonton Alberta with results written up above. At present Mr. Matuschka has funded all research here in the US at his LIPUS foundation's location in Colorado.


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An email from I.B.

I have had a very good dream about LIPUS the other night, and want to take a moment to inquire about
progress on a device for me. Also: yet another thank you for the suggestion of using toothpaste containing A. C. P.; it has made a noticeable improvement in tooth sensitivity. With best wishes for the new year, I. B.

Hi there,
 Thanks for dispatching the LIPUS device so quickly! The timing was 
excellent as I just had a hefty mercury filling removed (no more 

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The contents of the LIPUS foundation website and responses are for informational purposes only. The information contained on our Website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. If you have any questions regarding a medical condition or illness, you should always seek the advice of your physician or other qualified health care professional. Never disregard professional medical advice or delay in seeking advice or treatment because of information you have read on our website. If you think that you may have a medical emergency or other condition that requires treatment, call your doctor or seek emergency help immediately. Reliance on any information provided by the Lipus Foundation is solely at your own risk.